26 February 2025, New Delhi: The group of PA-Fungicides, also referred to as phenylamides, plays an important role in the fight against fungal diseases caused by Oomycetes pathogens. By inhibiting RNA polymerase I, phenylamides disrupt the ability of the pathogens to produce RNA, preventing their growth and reproduction. This makes them highly effective for managing diseases like downy mildew and late blight.
Despite their efficacy, resistance to phenylamides has become a significant concern. The mechanism of resistance remains elusive, but it’s known that Oomycetes pathogens can evolve to bypass the effects of these fungicides. Therefore, resistance management strategies such as alternating fungicides with different modes of action and applying them based on disease pressure are essential to prevent the rapid spread of resistant strains.
Farmers using phenylamides should incorporate these resistance management techniques to ensure these fungicides remain effective for years to come.
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